The status of Lorentz- and CPT-violation searches using measurements of the anomalous magnetic moment of the muon is reviewed. Results from muon g-2 experiments have set the majority of the most stringent limits on Standard- Model Extension Lorentz and CPT violation in the muon sector. These limits are consistent with calculations of the level of Standard-Model Extension effects required to account for the current 3.7{sigma} experiment-theory discrepancy in the muons g-2. The prospects for the new Muon g-2 Experiment at Fermilab to improve upon these searches is presented.