We report the Fermi Large Area Telescope (LAT) detections of high-energy (>100 MeV) gamma-ray emission from two recent optically bright classical novae, V1369 Centauri 2013 and V5668 Sagittarii 2015. At early times, Fermi target-of-opportunity observations prompted by their optical discoveries provided enhanced LAT exposure that enabled the detections of gamma-ray onsets beginning ~2 days after their first optical peaks. Significant gamma-ray emission was found extending to 39-55 days after their initial LAT detections, with systematically fainter and longer duration emission compared to previous gamma-ray detected classical novae. These novae were distinguished by multiple bright optical peaks that encompassed the timespans of the observed gamma rays. The gamma-ray light curves and spectra of the two novae are presented along with representative hadronic and leptonic models, and comparisons to other novae detected by the LAT are discussed.