We investigate the case of CII 158 micron observations for SPICA/SAFARI using a three-dimensional magnetohydrodynamical (MHD) simulation of the diffuse interstellar medium (ISM) and the Meudon PDR code. The MHD simulation consists of two converging flows of warm gas (10,000 K) within a cubic box 50 pc in length. The interplay of thermal instability, magnetic field and self-gravity leads to the formation of cold, dense clumps within a warm, turbulent interclump medium. We sample several clumps along a line of sight through the simulated cube and use them as input density profiles in the Meudon PDR code. This allows us to derive intensity predictions for the CII 158 micron line and provide time estimates for the mapping of a given sky area.