The antisymmetrized molecular dynamics (AMD) simulations suggest that the isospin composition of fragments produced dynamically in multifragmentation reactions is basically governed by the symmetry energy of low-density uniform nuclear matter rather than the symmetry energy for the ground-state finite nuclei. After the statistical secondary decay of the excited fragments, the symmetry energy effect still remains in the fragment isospin composition, though the effect in the isoscaling parameter seems a very delicate problem.
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