We investigate the geometrical and physical structures of a pseudo-symmetric spacetime $(PS)_4$ with timelike vector under the condition of conformal flatness. We classify it into two possible types: constant Ricci scalar and closed velocity vector. We further study this spacetime as a solution of $F(R)$-gravity theory and show that the pressure and energy density of the effective cosmological perfect fluid separately possess certain typical relations with the geometry and the gravity sector of the theory. Based on this result, some observational and cosmological analyses are done for the $F(R)$-gravity model and the energy conditions are investigated, supporting the accelerated expansion of the universe.