We study the degenerate Kolmogorov equations (also known as kinetic Fokker-Planck equations) in nondivergence form. The leading coefficients $a^{ij}$ are merely measurable in $t$ and satisfy the vanishing mean oscillation (VMO) condition in $x, v$ with respect to some quasi-metric. We also assume boundedness and uniform nondegeneracy of $a^{ij}$ with respect to $v$. We prove global a priori estimates in weighted mixed-norm Lebesgue spaces and solvability results. We also show an application of the main result to the Landau equation. Our proof does not rely on any kernel estimates.
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