In this paper, we aim to explore optimal regional trajectory tracking control problems of the anomalous subdiffusion processes governed by time-fractional diffusion systems under the Neumann boundary conditions. Using eigenvalue theory of the system operator and the semigroup theory, we explore the existence and some estimates of the mild solution to the considered system. An approach on finding solution to the optimal problem that minimizes the regional trajectory tracking error and the corresponding control cost over a finite space and time domain is then explored via the Hilbert uniqueness method (HUM). The obtained results not only can be directly used to investigate the systems that are not controllable on the whole domain, but also yield an explicit expression of the control signal in terms of the desired trajectory. Most importantly, it is worth noting that our results in this paper are still novel even for the special case when the order of fractional derivative is equal to one. Finally, we provide a numerical example to illustrate our theoretical results.
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