This paper is build around the stationary anisotropic Stokes and Navier-Stokes systems with an $L^infty$-tensor coefficient satisfying an ellipticity condition in terms of symmetric matrices in ${mathbb R}^{ntimes n}$ with zero matrix traces. We analyze, in $L^2$-based Sobolev spaces, the non-homogeneous boundary value problems of Dirichlet-transmission type for the anisotropic Stokes and Navier-Stokes systems in a compressible framework in a bounded Lipschitz domain with a Lipschitz interface in ${mathbb R}^n$, $nge 2$ ($n=2,3$ for the nonlinear problems). The transversal interface intersects the boundary of the Lipschitz domain. First, we use a mixed variational approach to prove well-posedness results for the linear anisotropic Stokes system. Then we show the existence of a weak solution for the nonlinear anisotropic Navier-Stokes system by implementing the Leray-Schauder fixed point theorem and using various results and estimates from the linear case, as well as the Leray-Hopf and some other norm inequalities. Explicit conditions for uniqueness of solutions to the nonlinear problems are also provided.