Coronal Mass Ejections (CMEs) are large-scale eruptions from the Sun into interplanetary space. Despite being major space weather drivers, our knowledge of the CME properties in the inner heliosphere remains constrained by the scarcity of observations at distances other than 1 au. Furthermore, most CMEs are observed in situ by single spacecraft, requiring numerical models to complement the sparse observations available. We aim to assess the ability of the linear force-free spheromak CME model in EUHFORIA to describe the radial evolution of interplanetary CMEs, yielding new context for observational studies. We model one well-studied CME, and investigate its radial evolution by placing virtual spacecraft along the Sun-Earth line in the simulation domain. To directly compare observational and modelling results, we characterise the interplanetary CME signatures between 0.2 and 1.9 au from modelled time series, exploiting techniques traditionally employed to analyse real in situ data. Results show that the modelled radial evolution of the mean solar wind and CME values is consistent with observational and theoretical expectations. The CME expands as a consequence of the decaying pressure in the surrounding wind: the expansion is rapid within 0.4 au, and moderate at larger distances. The early rapid expansion could not explain the overestimated CME radial size in our simulation, suggesting this is an intrinsic limitation of the spheromak geometry used. The magnetic field profile indicates a relaxation of the CME during propagation, while ageing is most probably not a substantial source of magnetic asymmetry beyond 0.4 au. We also report a CME wake that is significantly shorter than suggested by observations. Overall, EUHFORIA provides a consistent description of the radial evolution of solar wind and CMEs; nevertheless, improvements are required to better reproduce the CME radial extension.