We study both divergence and non-divergence form parabolic and elliptic equations in the half space ${x_d>0}$ whose coefficients are the product of $x_d^alpha$ and uniformly nondegenerate bounded measurable matrix-valued functions, where $alpha in (-1, infty)$. As such, the coefficients are singular or degenerate near the boundary of the half space. For equations with the conormal or Neumann boundary condition, we prove the existence, uniqueness, and regularity of solutions in weighted Sobolev spaces and mixed-norm weighted Sobolev spaces when the coefficients are only measurable in the $x_d$ direction and have small mean oscillation in the other directions in small cylinders. Our results are new even in the special case when the coefficients are constants, and they are reduced to the classical results when $alpha =0$