Instrumental variables (IV) regression is a popular method for the estimation of the endogenous treatment effects. Conventional IV methods require all the instruments are relevant and valid. However, this is impractical especially in high-dimensional models when we consider a large set of candidate IVs. In this paper, we propose an IV estimator robust to the existence of both the invalid and irrelevant instruments (called R2IVE) for the estimation of endogenous treatment effects. This paper extends the scope of Kang et al. (2016) by considering a true high-dimensional IV model and a nonparametric reduced form equation. It is shown that our procedure can select the relevant and valid instruments consistently and the proposed R2IVE is root-n consistent and asymptotically normal. Monte Carlo simulations demonstrate that the R2IVE performs favorably compared to the existing high-dimensional IV estimators (such as, NAIVE (Fan and Zhong, 2018) and sisVIVE (Kang et al., 2016)) when invalid instruments exist. In the empirical study, we revisit the classic question of trade and growth (Frankel and Romer, 1999).
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