In this paper we collect some open set-theoretic problems that appear in the large-scale topology (called also Asymptology). In particular we ask problems about critical cardinalities of some special (large, indiscrete, inseparated) coarse structures on $omega$, about the interplay between properties of a coarse space and its Higson corona, about some special ultrafilters ($T$-points and cellular $T$-points) related to finitary coarse structures on $omega$, about partitions of coarse spaces into thin pieces, and also about coarse groups having some extremal properties.
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