In this paper we investigate the asymptotic dynamics of inflationary cosmological models that are based in scalar-tensor theories of gravity. Our main aim is to explore the global structure of the phase space in the framework of single-field inflation models. For this purpose we make emphasis in the adequate choice of the variables of the phase space. Our results indicate that, although single-field inflation is generic in the sense that the corresponding critical point in the phase space exists for a wide class of potentials, along given phase space orbits -- representing potential cosmic histories -- the occurrence of the inflationary stage is rather dependent on the initial conditions. We have been able to give quantitative estimates of the relative probability (RP) for initial conditions leading to slow-roll inflation. For the non-minimal coupling model with the $phi^2$-potential our rough estimates yield to an almost vanishing relative probability: $10^{-13},%lesssim RPll 10^{-8},%$. These bonds are greatly improved in the scalar-tensor models, including the Brans-Dicke theory, where the relative probability $1,%lesssim RPleq 100,%$. Hence slow-roll inflation is indeed a natural stage of the cosmic expansion in Brans-Dicke models of inflation. It is confirmed as well that the dynamics of vacuum Brans-Dicke theories with arbitrary potentials are non-chaotic.