The interaction of heavy flavor with the quark-gluon plasma (QGP) in relativistic heavy-ion collisions is studied using JETSCAPE, a publicly available software package containing a framework for Monte Carlo event generators. Multi-stage (and multi-model) evolution of heavy quarks within JETSCAPE provides a cohesive description of heavy flavor quenching inside the QGP. As the parton shower develops, a model becomes active as soon as its kinematic region of validity is reached. Two combinations of heavy-flavor energy-loss models are explored within a realistic QGP medium, using parameters which were tuned to describe {it light-flavor} partonic energy-loss.