In [1, 2], Nekrasov applied the Bethe/gauge correspondence to derive the $mathfrak{su}, (2)$ XXX spin-chain coordinate Bethe wavefunction from the IR limit of a 2D $mathcal{N}=(2, 2)$ supersymmetric $A_1$ quiver gauge theory with an orbifold-type codimension-2 defect. Later, Bullimore, Kim and Lukowski implemented Nekrasovs construction at the level of the UV $A_1$ quiver gauge theory, recovered his result, and obtained further extensions of the Bethe/gauge correspondence [3]. In this work, we extend the construction of the defect to $A_M$ quiver gauge theories to obtain the $mathfrak{su} , ( M + 1 )$ XXX spin-chain nested coordinate Bethe wavefunctions. The extension to XXZ spin-chain is straightforward. Further, we apply a Higgsing procedure to obtain more general $A_M$ quivers and the corresponding wavefunctions, and interpret this procedure (and the Hanany-Witten moves that it involves) on the spin-chain side in terms of Izergin-Korepin-type specializations (and re-assignments) of the parameters of the coordinate Bethe wavefunctions.