There are four models of tree-level new physics (NP) that can potentially explain the $bto s mu^+ mu^-$ and $b to cell bar u$ anomalies simultaneously. They are the S3, U3, and U1 leptoquarks and a standard-model-like triplet vector boson (VB). In this talk, I describe an analysis of these models with general couplings. We find that even in this most general case S3 and U3 are excluded. For the U1 model, I discuss the importance of the constraints from lepton-flavor-violating(LFV) processes. As for the VB model, it is shown to be excluded by the additional tree level constraints and LHC bounds on high-mass resonant dimuon pairs. This conclusion is reached without any assumptions about the NP couplings.
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