The efficient certification of nonclassical effects of light forms the basis for applications in optical quantum technologies. We derive general correlation conditions for the verification of nonclassical light based on multiplexed detection. The obtained nonclassicality criteria are valid for imperfectly-balanced multiplexing scenarios with on-off detectors and do not require any knowledge about the detector system. In this sense they are fully independent of the detector system. In our experiment, we study light emitted by clusters of single-photon emitters, whose photon number may exceed the number of detection channels. Even under such conditions, our criteria certify nonclassicality with high statistical significance.