We study the quantum critical phenomena emerging at the transition from triple-Weyl semimetal to band insulator, which is a topological phase transition described by the change of topological invariant. The critical point realizes a new type of semimetal state in which the fermion dispersion is cubic along two directions and quadratic along the third. Our renormalization group analysis reveals that, the Coulomb interaction is marginal at low energies and even arbitrarily weak Coulomb interaction suffices to induce an infrared fixed point. We compute a number of observable quantities, and show that they all exhibit non-Fermi liquid behaviors at the fixed point. When the interplay between the Coulomb and short-range four-fermion interactions is considered, the system becomes unstable below a finite energy scale. The system undergoes a first-order topological transition when the fermion flavor $N$ is small, and enters into a nematic phase if $N$ is large enough. Non-Fermi liquid behaviors are hidden by the instability at low temperatures, but can still be observed at higher temperatures. Experimental detection of the predicted phenomena is discussed.
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