We generalize Quillens $F$-isomorphism theorem, Quillens stratification theorem, the stable transfer, and the finite generation of cohomology rings from finite groups to homotopical groups. As a consequence, we show that the category of module spectra over $C^*(Bmathcal{G},mathbb{F}_p)$ is stratified and costratified for a large class of $p$-local compact groups $mathcal{G}$ including compact Lie groups, connected $p$-compact groups, and $p$-local finite groups, thereby giving a support-theoretic classification of all localizing and colocalizing subcategories of this category. Moreover, we prove that $p$-compact groups admit a homotopical form of Gorenstein duality.