We introduce a natural nondegeneracy condition for Poisson structures, called holonomicity, which is closely related to the notion of a log symplectic form. Holonomic Poisson manifolds are privileged by the fact that their deformation spaces are as finite-dimensional as one could ever hope: the corresponding derived deformation complex is a perverse sheaf. We develop some basic structural features of these manifolds, highlighting the role played by the divergence of Hamiltonian vector fields. As an application, we establish the deformation-invariance of certain families of Poisson manifolds defined by Feigin and Odesskii, along with the elliptic algebras that quantize them.