The Gamma-Ray Imager/Polarimeter for Solar flares (GRIPS) is a balloon-borne telescope designed to study solar-flare particle acceleration and transport. We describe GRIPSs first Antarctic long-duration flight in Jan 2016 and report preliminary calibration and science results. Electron and ion dynamics, particle abundances and the ambient plasma conditions in solar flares can be understood by examining hard X-ray (HXR) and gamma-ray emission (20 keV to 10 MeV) with enhanced imaging, spectroscopy and polarimetry. GRIPS is specifically designed to answer questions including: What causes the spatial separation between energetic electrons producing HXRs and energetic ions producing gamma-ray lines? How anisotropic are the relativistic electrons, and why can they dominate in the corona? How do the compositions of accelerated and ambient material vary with space and time, and why? GRIPSs key technological improvements over the Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI) include 3D position-sensitive germanium detectors (3D-GeDs) and a single-grid, multi-pitch rotating modulator (MPRM) collimator. The 3D-GeDs have spectral FWHM resolution of a few hundred keV and spatial resolution $<$1 mm$^3$. For photons that Compton scatter, usually $gtrsim$150 keV, the energy deposition sites can be tracked, providing polarization measurements as well as enhanced background reduction. The MPRM single-grid design provides twice the throughput of a bi-grid imaging system like RHESSI. The grid is composed of 2.5 cm thick W/Cu slats with 1-13 mm variable slit pitch, achieving quasi-continuous FWHM angular coverage over 12.5-162 arcsecs. This resolution is capable of imaging the separate magnetic loop footpoint emissions in a variety of flare sizes. (Abstract edited down from source.)