We consider the entanglement between two spatial subregions in the Lieb-Liniger model of bosons in one spatial dimension interacting via a contact interaction. Using ground state path integral quantum Monte Carlo we numerically compute the R{e}nyi entropy of the reduced density matrix of the subsystem as a measure of entanglement. Our numerical algorithm is based on a replica method previously introduced by the authors, which we extend to efficiently study the entanglement of spatial subsystems of itinerant bosons. We confirm a logarithmic scaling of the R{e}nyi entropy with subsystem size that is expected from conformal field theory, and compute the non-universal subleading constant for interaction strengths ranging over two orders of magnitude. In the strongly interacting limit, we find agreement with the known free fermion result.
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