We demonstrate ground-state cooling of a trapped ion using radio-frequency (RF) radiation. This is a powerful tool for the implementation of quantum operations, where RF or microwave radiation instead of lasers is used for motional quantum state engineering. We measure a mean phonon number of $overline{n} = 0.13(4)$ after sideband cooling, corresponding to a ground-state occupation probability of 88(7)%. After preparing in the vibrational ground state, we demonstrate motional state engineering by driving Rabi oscillations between the n=0 and n=1 Fock states. We also use the ability to ground-state cool to accurately measure the motional heating rate and report a reduction by almost two orders of magnitude compared to our previously measured result, which we attribute to carefully eliminating sources of electrical noise in the system.