We establish the phase diagram of the strongly-interacting Bose-Hubbard model defined on a two-leg ladder geometry in the presence of a homogeneous flux. Our work is motivated by a recent experiment [Atala et al., Nature Phys. 10, 588 (2014)], which studied the same system, in the complementary regime of weak interactions. Based on extensive density matrix renormalization group simulations and a bosonization analysis, we fully explore the parameter space spanned by filling, inter-leg tunneling, and flux. As a main result, we demonstrate the existence of gapless and gapped Meissner and vortex phases, with the gapped states emerging in Mott-insulating regimes. We calculate experimentally accessible observables such as chiral currents and vortex patterns.
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