Results are presented for the momentum dependent two-loop contributions of O(alpha_t alpha_s) to the masses and mixing effects in the Higgs sector of the MSSM. They are obtained in the Feynman-diagrammatic approach using a mixed on-shell/DRbar renormalization that can directly be matched onto the higher-order corrections included in the code FeynHiggs. The new two-loop diagrams are evaluated with the program SecDec. The combination of the new momentum dependent two-loop contribution with the existing one- and two-loop corrections in the on-shell/DRbar scheme leads to an improved prediction of the light MSSM Higgs boson mass and a correspondingly reduced theoretical uncertainty. We find that the corresponding shifts in the lightest Higgs-boson mass M_h are below 1 GeV in all scenarios considered, but can extend up to the level of the current experimental uncertainty. The results are included in the code FeynHiggs.