The proximity effect (PE) between superconductor and confined electrons can induce the effective pairing phenomena of electrons in nanowire or quantum dot (QD). Through interpreting the PE as an exchange of virtually quasi-excitation in a largely gapped superconductor, we found that there exists another induced dynamic process. Unlike the effective pairing that mixes the QD electron states coherently, this extra process leads to dephasing of the QD. In a case study, the dephasing time is inversely proportional to the Coulomb interaction strength between two electrons in the QD. Further theoretical investigations imply that this dephasing effect can decrease the quality of the zero temperature mesoscopic electron transportation measurements by lowering and broadening the corresponding differential conductance peaks.