In performing a Bayesian analysis, two difficult problems often emerge. First, in estimating the parameters of some model for the data, the resulting posterior distribution may be multi-modal or exhibit pronounced (curving) degeneracies. Secondly, in selecting between a set of competing models, calculation of the Bayesian evidence for each model is computationally expensive using existing methods such as thermodynamic integration. Nested Sampling is a Monte Carlo method targeted at the efficient calculation of the evidence, but also produces posterior inferences as a by-product and therefore provides means to carry out parameter estimation as well as model selection. The main challenge in implementing Nested Sampling is to sample from a constrained probability distribution. One possible solution to this problem is provided by the Galilean Monte Carlo (GMC) algorithm. We show results of applying Nested Sampling with GMC to some problems which have proven very difficult for standard Markov Chain Monte Carlo (MCMC) and down-hill methods, due to the presence of large number of local minima and/or pronounced (curving) degeneracies between the parameters. We also discuss the use of Nested Sampling with GMC in Bayesian object detection problems, which are inherently multi-modal and require the evaluation of Bayesian evidence for distinguishing between true and spurious detections.
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