The Standard Model (SM) of particle physics fails to explain dark matter and why matter survived annihilation with antimatter following the Big Bang. Extensions to the SM, such as weak-scale Supersymmetry, may explain one or both of these phenomena by positing the existence of new particles and interactions that are asymmetric under time-reversal (T). These theories nearly always predict a small, yet potentially measurable ($10^{-27}$-$10^{-30}$ $e$ cm) electron electric dipole moment (EDM, $d_e$), which is an asymmetric charge distribution along the spin ($vec{S}$). The EDM is also asymmetric under T. Using the polar molecule thorium monoxide (ThO), we measure $d_e = (-2.1 pm 3.7_mathrm{stat} pm 2.5_mathrm{syst})times 10^{-29}$ $e$ cm. This corresponds to an upper limit of $|d_e| < 8.7times 10^{-29}$ $e$ cm with 90 percent confidence, an order of magnitude improvement in sensitivity compared to the previous best limits. Our result constrains T-violating physics at the TeV energy scale.