A universal approach is proposed for suppression of collective synchrony in a large population of interacting rhythmic units. We demonstrate that provided that the internal coupling is weak, stabilization of overall oscillations with vanishing stimulation leads to desynchronization in a large ensemble of coupled oscillators, without altering significantly the essential nature of each constituent oscillator. We expect our findings to be a starting point for the issue of destroying undesired synchronization, e. g. desynchronization techniques for deep brain stimulation for neurological diseases characterized by pathological neural synchronization.
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