Dwarf spheroidal galaxies have a large mass to light ratio and low astrophysical background, and are therefore considered one of the most promising targets for dark matter searches in the gamma-ray band. By applying a joint likelihood analysis, the power of resultant limits in case of no detection can be enhanced and robust constraints on the dark matter parameter space can be obtained. We present results from a combined analysis of 10 dwarf spheroidal galaxies using Fermi-LAT data. Different annihilation channels have been analyzed and uncertainties from astrophysical properties have been taken into account.