Prospective presentation is given for the experimental program of the KLOE-2 Collaboration, to be performed using the DA$Phi$NE $e^+e^-$ collider upgraded in luminosity. Data with the total luminosity of 25 fb$^{-1}$ are aimed to be collected in 3 years. Major modifications of the accelerator and the spectrometer are described. The KLOE-2 physics program contains: CKM unitarity and lepton universality tests, $gammagamma$ physics, search for quantum decoherence and testing CPT conservation, low-energy QCD, rare kaon decays, physics of $eta$ and $eta^prime$, structure of low-mass scalars, contribution of vacuum polarization to $(g-2)_{mu}$, possible search for WIMP dark matter. In this paper only selected physics subjects are reported.
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