We take two new approaches to design efficient algorithms for transmitter optimization under rate constraints, to guarantee the Quality of Service in general MIMO interference networks, which is a combination of multiple interfering broadcast channels (BC) and multiaccess channels (MAC) and is named B-MAC Networks. Two related optimization problems, maximizing the minimum of weighted rates under a sum-power constraint and minimizing the sum-power under rate constraints, are considered. The first approach takes advantage of existing efficient algorithms for SINR problems by building a bridge between rate and SINR through the design of optimal mappings between them. The approach can be applied to other optimization problems as well. The second approach employs polite water-filling, which is the optimal network version of water-filling that we recently found. It replaces most generic optimization algorithms currently used for networks and reduces the complexity while demonstrating superior performance even in non-convex cases. Both centralized and distributed algorithms are designed and the performance is analyzed in addition to numeric examples.