We discuss observational evidence that quasars play a key role in the formation of galaxies starting from the detailed study of the quasar HE0450-2958 and extending the discussion to a series of converging evidence that radio jets may trigger galaxy formation. The direct detection with VISIR at the ESO-VLT of the 7 kpc distant companion galaxy of HE0450-2958 allows us to spatially separate the sites of quasar and star formation activity in this composite system made of two ultra-luminous infrared galaxies (ULIRGs). No host galaxy has yet been detected for this quasar, but the companion galaxy stellar mass would bring HE0450-2958 in the local M(BH)-M(stellar bulge) relation if it were to merge with the QSO. This is bound to happen because of their close distance (7 kpc) and small relative velocity (~60-200 km/s). We conclude that we may be witnessing the building of the M(BH)-M(stellar bulge) relation, or at least of a major event in that process. The star formation rate (~340 Msun/yr), age (40-200 Myr) and stellar mass ([5-6]x10^10 Msun) are consistent with jet-induced formation of the companion galaxy. We suggest that HE0450-2958 may be fueled in fresh material by cold gas accretion from intergalactic filaments. We map the projected galaxy density surrounding the QSO as a potential tracer of intergalactic filaments and discuss a putative detection. Comparison to other systems suggests that inside-out formation of quasar host galaxies and jet-induced galaxy formation may be a common process. Two tests are proposed for this new paradigm: (1) the detection of offset molecular gas or dust emission with respect to the position of distant QSOs, (2) the delayed formation of host galaxies as a result of QSO activity, hence the two step building of the M(BH)/M(stellar bulge) ratio.
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