We consider a homogeneous 2D Bose gas with repulsive dipole-dipole interactions. The ground-state equation of state, calculated using the Diffusion Monte Carlo method, shows quantitative differences with predictions of commonly used Gross-Pitaevskii mean-field theory. The static structure factor, pair distribution function and condensate fraction are calculated in a wide range of the gas parameter. Differences with mean-field theory are reflected in the frequency of the lowest ``breathing mode for harmonically trapped systems.