We report the serendipitous discovery of the Sloan Digital Sky Survey star, SDSS J160043.6+074802.9 to be a very rapid pulsator. The variation is dominated by a frequency near 8380 microHz (period = 119.33 s) with a large amplitude (0.04 mag) and its first harmonic at 16760 microHz (59.66 s; 0.005 mag). In between these frequencies, we find at least another 8 variations with periods between 62 and 118 seconds and amplitudes between about 0.007 and 0.003 mag; weaker oscillations might also be present. Preliminary spectrograms from the performance verification phase of the Southern African Large Telescope indicate that SDSS J160043.6+074802.9 is a spectroscopic binary consisting of an sdO star and a late-type main-sequence companion. This makes it the first unambiguous detection of such an sdO star to pulsate, and certainly the first found to exhibit multi-frequency variations.