The observational consequences of the merger scenario for massive star formation are explored and contrasted with the gradual accumulation of mass by accretion. Protostellar mergers may produce high luminosity infrared flares lasting years to centuries followed by a luminosity decline on the Kelvin-Helmholtz time-scale of the merger product. Mergers may be surrounded by thick tori of expanding debris, impulsive wide-angle outflows, and shock induced maser and radio continuum emission. Collision products are expected to have fast stellar rotation and a large multiplicity fraction. Close encounters or mergers will produce circumstellar debris disks with an orientation that differs form that of a pre-existing disk. The extremely rare merger of two stars close to the upper-mass end of the IMF may be a possible pathway to hypernova generated gamma-ray bursters. While accretional growth can lead to the formation of massive stars in isolation or in loose clusters, mergers can only occur in high-density cluster environments. It is proposed that the outflow emerging from the OMC1 core in the Orion molecular cloud was produced by a protostellar merger that released between $10^{48}$ to $10^{49}$ ergs less than a thousand years ago.