We briefly review some recent results from Chandra and XMM-Newton studies of the highest redshift (z > 4) active galactic nuclei (AGNs). Specific topics covered include radio-quiet quasars, radio-loud quasars, moderate-luminosity AGNs in X-ray surveys, and future prospects. No significant changes in AGN X-ray emission properties have yet been found at high redshift, indicating that the small-scale X-ray emission regions of AGNs are insensitive to the dramatic changes on larger scales that occur from z = 0-6. X-ray observations are also constraining the environments of high-redshift AGNs, relevant emission processes, and high-redshift AGN demography.