Current X-ray observatories, archival X-ray data, and the Sloan Digital Sky Survey (SDSS) represent a powerful combination for addressing key questions about active galactic nuclei (AGN). We describe a few selected issues at the forefront of X-ray AGN research and the relevance of the SDSS to them. Bulk X-ray/SDSS AGN investigations, X-ray weak AGN, red AGN, hard X-ray selected AGN, high-redshift AGN demography, and future prospects are all briefly discussed.