Quivers, gauge theories and singular geometries are of great interest in both mathematics and physics. In this note, we collect a few open questions which have arisen in various recent works at the intersection between gauge theories, representation theory, and algebraic geometry. The questions originate from the study of supersymmetric gauge theories in different dimensions with different supersymmetries. Although these constitute merely the tip of a vast iceberg, we hope this guide can give a hint of possible directions in future research. This is an invited contribution to a special volume of Proyecciones, E. Gasparim, Ed., and it is the hope that the questions are specific enough for research projects aimed at PhD students.
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