The nonlinear and nonlocal coupling of vorticity and strain-rate constitutes a major hindrance in understanding the self-amplification of velocity gradients in turbulent fluid flows. Utilizing highly-resolved direct numerical simulations of isotropic turbulence in periodic domains of up to $12288^3$ grid points, and Taylor-scale Reynolds number $R_lambda$ in the range $140-1300$, we investigate this non-locality by decomposing the strain-rate tensor into local and non-local contributions obtained through Biot-Savart integration of vorticity in a sphere of radius $R$. We find that vorticity is predominantly amplified by the non-local strain coming beyond a characteristic scale size, which varies as a simple power-law of vorticity magnitude. The underlying dynamics preferentially align vorticity with the most extensive eigenvector of non-local strain. The remaining local strain aligns vorticity with the intermediate eigenvector and does not contribute significantly to amplification; instead it surprisingly attenuates intense vorticity, leading to breakdown of the observed power-law and ultimately also the scale-invariance of vorticity amplification, with important implications for prevailing intermittency theories.
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