There are no valid points of criticism in Tyshkovskiy and Panchins response (10.1002/bies.202000325) to our paper The genetic structure of SARS-CoV-2 does not rule out a laboratory origin (DOI: 10.1002/bies.202000240)


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Tyshkovskiy and Panchin have recently published a commentary on our paper in which they outline several points of disagreement with the Segreto/Deigin hypothesis. As our paper is titled The genetic structure of SARS-CoV-2 does not rule out a laboratory origin, points of disagreement should provide evidence that rules out a laboratory origin. However, Tyshkovskiy and Panchin provide no such evidence and instead attempt to criticize our arguments that highlight aspects of SARS-CoV-2 that could be consistent with the lab leak hypothesis. Strikingly, Tyshkovskiy and Panchins main point of criticism is based on a false premise that we have claimed RaTG13 to be a direct progenitor of SARS-CoV-2, and their other points of criticism are either incorrect or irrelevant to our hypotheses. Thus, the genetic structure of SARS-CoV-2 remains consistent with both natural or laboratory origin, which means that both the zoonotic and the lab leak hypothesis need to be investigated equally thoroughly.

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