The observation of cosmic microwave background (CMB) anisotropies is one of the key probes of physical cosmology. The weak nature of this signal has driven the construction of increasingly complex and sensitive experiments observing the sky at multiple frequencies with thousands of polarization sensitive detectors. Given the high sensitivity of such experiments, instrumental systematic effects can become the limiting factor towards the full scientific exploitation of their data. In this paper we present s4cmb (Systematics for CMB), a Python package designed to simulate raw data streams in time domain of modern CMB experiments based on bolometric technology, and to inject in these realistic instrumental systematics effects. The aim of the package is to help assessing the contamination due to instrumental systematic effects on real data, to guide the design of future instruments, as well as to increase the realism of simulated data sets required in the development of accurate data analysis methods.
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