We consider a cosmological scenario endowed with an interaction between the universes dark components $-$ dark matter and dark energy. Specifically, we assume the dark matter component to be a pressure-less fluid, while the dark energy component is a quintessence scalar field with Lagrangian function modified by the quadratic Generalized Uncertainty Principle. The latter modification introduces new higher-order terms of fourth-derivative due to quantum corrections in the scalar fields equation of motion. Then we investigate asymptotic dynamics and general behaviour of solutions of the field equations for some interacting models of special interests in the literature. At the background level, the present interacting model exhibits the matter-dominated and de Sitter solutions which are absent in the corresponding quintessence model. Furthermore, to boost the background analysis, we study cosmological linear perturbations in the Newtonian gauge where we show how perturbations are modified by quantum corrected terms from the quadratic Generalized Uncertainty Principle. Depending on the coupling parameters, scalar perturbations show a wide range of behavior.
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