From ancient to modern times, acoustic structures have been used to control the propagation of acoustic waves. However, the design of the acoustic structures has remained widely a time-consuming and computational resource-consuming iterative process. In recent years, Deep Learning has attracted unprecedented attention for its ability to tackle hard problems with huge datasets, which has achieved state-of-the-art results in various tasks. In this work, an acoustic structure design method is proposed based on deep learning. Taking the design of multi-order Helmholtz resonator for instance, we experimentally demonstrate the effectiveness of the proposed method. Our method is not only able to give a very accurate prediction of the geometry of the acoustic structures with multiple strong-coupling parameters, but also capable of improving the performance of evolutionary approaches in optimization for a desired property. Compared with the conventional numerical methods, our method is more efficient, universal and automatic, which has a wide range of potential applications, such as speech enhancement, sound absorption and insulation.