A great variety of novel phenomena occur when two-dimensional materials, such as graphene or transition metal dichalcogenides, are assembled into bilayers with a twist between individual layers. As a new application of this paradigm, we consider structures composed of two monolayer-thin $d$-wave superconductors with a twist angle $theta$ that can be realized by mechanically exfoliating van der Waals-bonded high-$T_c$ copper oxide materials, such as Bi$_2$Sr$_2$CaCu$_2$O$_{8+delta}$. On the basis of symmetry arguments and detailed microscopic modelling, we predict that for a range of twist angles in the vicinity of $45^{rm o}$, such bilayers form a robust, fully gapped topological phase with spontaneously broken time-reversal symmetry and protected chiral Majorana edge modes. When $thetaapprox 45^{rm o}$, the topological phase sets in at temperatures close to the bulk $T_csimeq 90$ K, thus furnishing a long sought realization of a true high-temperature topological superconductor.