Using a low-energy effective field theory approach, we study some properties of models with large extra dimensions, in which quarks and leptons have localized wave functions in the extra dimensions. We consider models with two types of gauge groups: (i) the Standard-Model gauge group, and (ii) the left-right symmetric (LRS) gauge group. Our main focus is on the lepton sector of models with $n=2$ extra dimensions, in particular, neutrino masses and mixing. We analyze the requisite conditions that the models must satisfy to be in accord with data and present a solution for lepton wave functions in the extra dimensions that fulfills these conditions. As part of our work, we also present a new solution for quark wave function centers. Issues with flavor-changing neutral current effects are assessed. Finally, we remark on baryogenesis and dark matter in these models.
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