Morrison, Walker, and Wedrich used the blob complex to construct a generalization of Khovanov-Rozansky homology to links in the boundary of a 4-manifold. The degree zero part of their theory, called the skein lasagna module, admits an elementary definition in terms of certain diagrams in the 4-manifold. We give a description of the skein lasagna module for 4-manifolds without 1- and 3-handles, and present some explicit calculations for disk bundles over $S^2$.