We investigate the response of 3D Luttinger semimetals to localized charge and spin impurities as a function of doping. The strong spin-orbit coupling of these materials strongly influences the Friedel oscillations and RKKY interactions. This can be seen at short distances with an $1/r^4$ divergence of the responses, and anisotropic behavior. Certain of the spin-orbital signatures are robust to temperature, even if the charge and spin oscillations are smeared out, and give an unusual diamagnetic Pauli susceptibility. We compare our results to the experimental literature on the bismuth-based half-Heuslers such as YPtBi and on the pyrochlore iridate Pr$_2$Ir$_2$O$_7$.
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