Entanglement plays a central role in quantum information processing, indicating the non-local correlation of quantum matters. However, few effective ways are known to detect the amount of entanglement of an unknown quantum state. In this work, we propose a scheme to estimate the entanglement negativity of any bi-partition of a composite system. The proposed scheme is based on the random unitary evolution and local measurements on the single-copy quantum states, which is more practical compared with former methods based on collective measurements on many copies of the identical state. Meanwhile, we generalize the scheme to quantify the total multi-partite correlation. We demonstrate the efficiency of the scheme with theoretical statistical analysis and numerical simulations. The proposed scheme is quite suitable for state-of-the-art quantum platforms, which can serve as not only a useful benchmarking tool to advance the quantum technology, but also a probe to study fundamental quantum physics, such as the entanglement dynamics.
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