We study the volume prescription of the holographic subregion complexity in a holographic 5 dimensional model consisting of Einstein gravity coupled to a scalar field with a non-trivial potential. The dual 4 dimensional gauge theory is not conformal and exhibits a RG flow between two different fixed points. In both zero and finite temperature we show that the holographic subregion complexity can be used as a measure of non-conformality of the model. This quantity exhibits also a monotonic behaviour in terms of the size of the entangling region, like the behaviour of the entanglement entropy in this setup. There is also a finite jump due to the disentangling transition between connected and disconnected minimal surfaces for holographic renormalized subregion complexity at zero temperature.